⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20552375 | 0.76 | OPRD1 (0.36) | — | |
| SCHEMBL23600136 | 0.71 | — | — | |
| SCHEMBL20552571 | 0.70 | ALDH1A1 (0.42) | — | |
| SCHEMBL3232288 | 0.68 | POLB (0.32) | — | |
| SCHEMBL3234662 | 0.67 | POLB (0.34) | — | |
| SCHEMBL20551793 | 0.65 | — | — | |
| SCHEMBL20552104 | 0.65 | ALDH1A1 (0.31) | — | |
| SCHEMBL20551508 | 0.63 | TSHR (0.34) | — | |
| SCHEMBL3232301 | 0.62 | — | — | |
| SCHEMBL30601853 | 0.61 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339174-B2 | γ-spiroketal-γ-lactones and pharmaceutical composition containing same and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-05-24 | — | — | US | claimed |
| EP-3619214-B1 | GAMMA-SPIROKETAL-GAMMA-LACTONES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PROCESS FOR PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2024-11-06 | — | — | EP | disclosed |
| US-11339174-B2 | γ-spiroketal-γ-lactones and pharmaceutical composition containing same and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-05-24 | — | — | US | disclosed |
| US-20210198273-A1 | GAMMA-SPIROKETAL-GAMMA-LACTONES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-07-01 | — | — | US | disclosed |
| EP-3619214-A1 | GAMMA-SPIROKETAL-GAMMA-LACTONES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PROCESS FOR PREPARATION THEREOF | Council of Scientific and Industrial Research (IN) | 2020-03-11 | — | — | EP | disclosed |
| WO-2018203346-A1 | γ-SPIROKETAL- γ –LACTONES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2018-11-08 | — | — | WO | disclosed |