Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 6/20 | 0.51 |
| ▸ | MDM4 | O15151 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18632610 | 1.00 | MDM2 (0.51) | MDM2MDM4TP53TLR2SLC17A5 | |
| SCHEMBL9511556 | 0.93 | MDM2 (0.49) | MDM2MDM4TP53TLR2SLC17A5 | |
| SCHEMBL9511552 | 0.93 | MDM2 (0.49) | MDM2MDM4TP53TLR2SLC17A5 | |
| SCHEMBL17079665 | 0.91 | SLC17A5 (0.53) | MDM2MDM4TP53TLR2SLC17A5 | |
| SCHEMBL29374829 | 0.90 | MDM2 (0.55) | MDM2MDM4TP53TLR2SLC17A5 | |
| SCHEMBL29768913 | 0.90 | MDM2 (0.55) | MDM2MDM4TP53TLR2SLC17A5 | |
| SCHEMBL29352017 | 0.90 | MDM2 (0.55) | MDM2MDM4TP53TLR2SLC17A5 | |
| SCHEMBL29792120 | 0.90 | MDM2 (0.55) | MDM2MDM4TP53TLR2SLC17A5 | |
| SCHEMBL117964 | 0.90 | MDM2 (0.55) | MDM2MDM4TP53TLR2SLC17A5 | |
| SCHEMBL120511 | 0.90 | MDM2 (0.55) | MDM2MDM4TP53TLR2SLC17A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3152225-B1 | PEPTIDES AS OXYTOCIN AGONISTS | HOFFMANN LA ROCHE (CH) | 2018-11-14 | — | — | EP | disclosed |
| CN-106459156-A | Peptides as oxytocin agonists | 豪夫迈·罗氏有限公司 | 2017-02-22 | — | — | CN | disclosed |