Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MDM4 | O15151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | TNF | P01375 | 3/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511552 | 1.00 | MDM2 (0.49) | MDM2IDO1MDM4TP53PPARG | |
| SCHEMBL18632610 | 0.93 | MDM2 (0.51) | MDM2MDM4TP53TNFTLR2 | |
| SCHEMBL20554036 | 0.93 | MDM2 (0.51) | MDM2MDM4TP53TNFTLR2 | |
| SCHEMBL29400768 | 0.90 | MDM2 (0.53) | MDM2IDO1MDM4TP53PPARG | |
| SCHEMBL14381107 | 0.90 | MDM2 (0.53) | MDM2IDO1MDM4TP53PPARG | |
| SCHEMBL10131781 | 0.90 | MDM2 (0.53) | MDM2IDO1MDM4TP53PPARG | |
| SCHEMBL9514163 | 0.86 | PPARG (0.51) | MDM2IDO1MDM4TP53PPARG | |
| SCHEMBL8350968 | 0.84 | IDO1 (0.53) | MDM2IDO1MDM4TP53PPARG | |
| SCHEMBL29401813 | 0.84 | IDO1 (0.53) | MDM2IDO1MDM4TP53PPARG | |
| SCHEMBL17079665 | 0.84 | SLC17A5 (0.53) | MDM2MDM4TP53PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320967-B1 | ANF derivatives with novel bridging | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1993-12-08 | — | — | EP | disclosed |
| US-4891358-A | ATRIAL NATRIURETIC FACTOR | BIO-MEGA INC. (CA) | 1990-01-02 | — | — | US | disclosed |
| EP-0320967-A2 | ANF derivatives with novel bridging | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1989-06-21 | — | — | EP | disclosed |