Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 13/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 10/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.52 |
| ▸ | PI4KA | P42356 | 4/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21539360 | 0.71 | ADORA2A (0.71) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL22300665 | 0.71 | ADORA2A (0.71) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL20014135 | 0.70 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL29280561 | 0.69 | ADORA2A (0.46) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL18510391 | 0.69 | ADORA2A (0.67) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL22381523 | 0.68 | ADORA2A (0.56) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL16707341 | 0.67 | ADORA2A (0.63) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL28432009 | 0.65 | NSD3 (0.60) | ADORA2AADORA1ADORA2BADORA3HSP90AA1 | |
| SCHEMBL28897799 | 0.65 | ADORA2A (0.50) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL22571151 | 0.65 | ADORA2A (0.70) | ADORA2AADORA1ADORA2BADORA3PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11541060-B2 | Pharmaceutical compositions for treating pain | Forever Cheer Holding Limited (HK) | 2023-01-03 | — | — | US | claimed |
| US-20180333420-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATING PAIN | FOREVER CHEER INTERNATIONAL LTD (HK) | 2018-11-22 | — | — | US | claimed |
| EP-3403674-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATING PAIN | Forever Cheer International Limited (HK) | 2018-11-21 | — | — | EP | claimed |
| US-11541060-B2 | Pharmaceutical compositions for treating pain | Forever Cheer Holding Limited (HK) | 2023-01-03 | — | — | US | disclosed |
| CN-108743589-B | Pharmaceutical composition for treating pain | 永展国际有限公司 | 2021-05-14 | — | — | CN | disclosed |
| US-20200268766-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATING PAIN | Forever Cheer Holding Limited (HK) | 2020-08-27 | — | — | US | disclosed |
| US-20180333420-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATING PAIN | FOREVER CHEER INTERNATIONAL LTD (HK) | 2018-11-22 | — | — | US | disclosed |
| EP-3403674-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATING PAIN | Forever Cheer International Limited (HK) | 2018-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268766-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATING PAIN | OPRM1, OPRL1, OPRD1 | ADORA2A 511/4885ADORA1 84/4885ADORA2B 335/4885 |
| US-11541060-B2 | Pharmaceutical compositions for treating pain | OPRM1, OPRL1, OPRD1 | ADORA2A 511/4885ADORA1 84/4885ADORA2B 335/4885 |
| US-20180333420-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATING PAIN | OPRM1, OPRL1, OPRD1 | ADORA2A 511/4885ADORA1 84/4885ADORA2B 335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.