SCHEMBL205604

SCHEMBL205604

CCCCCCCCNc1ccc(N)c(C)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.56
ALDH1A1 P00352 3/20 0.50
SKP2 Q13309 1/20 0.49
CYP3A4 P08684 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
THRB P10828 1/20 0.44
ALOX15 P16050 1/20 0.44
RECQL P46063 1/20 0.44
HIF1A Q16665 1/20 0.44
S100B P04271 1/20 0.42
ADRA2A P08913 1/20 0.40
KCNH3 Q9ULD8 1/20 0.40
PLK1 P53350 3/20 0.40
EPHX2 P34913 1/20 0.40
HTT P42858 1/20 0.39
BACE1 P56817 1/20 0.39
TSHR P16473 1/20 0.38
CNR2 P34972 1/20 0.38
F2 P00734 1/20 0.38
PRSS1 P07477 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10406890 1.00 ABL1 (0.56) ABL1ALDH1A1SKP2CYP3A4TDP1
SCHEMBL6369975 0.93 ALDH1A1 (0.56) ABL1ALDH1A1SKP2CYP3A4TDP1
SCHEMBL6369929 0.93 ALDH1A1 (0.56) ABL1ALDH1A1SKP2CYP3A4TDP1
Hydrochloric Acid SCHEMBL4954707 0.91 ALDH1A1 (0.54) ABL1ALDH1A1SKP2CYP3A4TDP1
Hydrochloric Acid SCHEMBL4949443 0.91 ALDH1A1 (0.54) ABL1ALDH1A1SKP2CYP3A4TDP1
SCHEMBL2933227 0.91 ALDH1A1 (0.58) ABL1ALDH1A1SKP2CYP3A4TDP1
SCHEMBL6376391 0.88 ALDH1A1 (0.53) ABL1ALDH1A1SKP2CYP3A4TDP1
SCHEMBL29262271 0.87 ABL1 (0.53) ABL1ALDH1A1SKP2TDP1ADRA2A
SCHEMBL29578255 0.86 ABL1 (0.55) ABL1ALDH1A1ADRA2AKCNH3PLK1
Hydrochloric Acid SCHEMBL4952474 0.86 ALDH1A1 (0.51) ABL1ALDH1A1SKP2CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3086158-A1 ELECTROWETTING ELEMENT Amazon Europe Holding Technologies SCS (LU) 2016-10-26 EP disclosed
EP-2162780-B1 IMPROVEMENTS IN RELATION TO ELECTROWETTING ELEMENTS AND OPTICAL DISPLAY DEVICES LIQUAVISTA BV (NL) 2016-07-06 EP disclosed
US-8199409-B2 Electrowetting elements and optical display devices SAMSUNG LCD NETHERLANDS R&D CENTER B.V. (NL) 2012-06-12 US disclosed
US-8088806-B2 Thiazole compounds and methods of use ACHILLION PHARMACEUTICALS, INC. (US) 2012-01-03 US disclosed
US-20100220380-A1 ELECTROWETTING ELEMENTS AND OPTICAL DISPLAY DEVICES LIQUAVISTA B.V. (NL) 2010-09-02 US disclosed