Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202175 | 0.89 | ALDH1A1 (0.47) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL2709340 | 0.88 | ALDH1A1 (0.46) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL2682720 | 0.87 | ALDH1A1 (0.47) | ALDH1A1LMNAHTTSMN1; SMN2RAB9A | |
| SCHEMBL204159 | 0.86 | KMT2A (0.49) | ALDH1A1LMNAHTTSMN1; SMN2GLA | |
| SCHEMBL2709571 | 0.86 | HTT (0.51) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL204433 | 0.82 | BCHE (0.47) | ALDH1A1LMNAHTTSMN1; SMN2GLA | |
| SCHEMBL671016 | 0.82 | ALDH1A1 (0.54) | ALDH1A1LMNAHTTSMN1; SMN2GLA | |
| SCHEMBL29642061 | 0.82 | ALDH1A1 (0.54) | ALDH1A1LMNAHTTSMN1; SMN2GLA | |
| SCHEMBL2707298 | 0.82 | KMT2A (0.55) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL2707375 | 0.81 | SMN1; SMN2 (0.52) | ALDH1A1LMNAHTTSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12077535-B2 | Derivatives of resiquimod | SUPERB WISDOM LIMITED (WS) | 2024-09-03 | — | — | US | disclosed |
| US-20230002370-A1 | DERIVATIVES OF RESIQUIMOD | SUPERB WISDOM LIMITED (WS) | 2023-01-05 | — | — | US | disclosed |
| US-20230002370-A1 | DERIVATIVES OF RESIQUIMOD | SUPERB WISDOM LIMITED (WS) | 2023-01-05 | — | — | US | disclosed |
| EP-3625231-B1 | DERIVATIVES OF RESIQUIMOD | SUPERB WISDOM LTD (WS) | 2022-07-20 | — | — | EP | disclosed |
| US-11274099-B2 | Derivatives of Resiquimod | SUPERB WISDOM LIMITED (WS) | 2022-03-15 | — | — | US | disclosed |
| US-20200207757-A1 | DERIVATIVES OF RESIQUIMOD | SUPERB WISDOM LIMITED (WS) | 2020-07-02 | — | — | US | disclosed |
| US-20200207757-A1 | DERIVATIVES OF RESIQUIMOD | SUPERB WISDOM LIMITED (WS) | 2020-07-02 | — | — | US | disclosed |
| EP-3625231-A1 | DERIVATIVES OF RESIQUIMOD | Superb Wisdom Limited (WS) | 2020-03-25 | — | — | EP | disclosed |
| WO-2018213769-A1 | DERIVATIVES OF RESIQUIMOD | SUPERB WISDOM LIMITED (WS) | 2018-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200207757-A1 | DERIVATIVES OF RESIQUIMOD | MYD88, TLR7, HLA-DRB1 | ALDH1A1 865/4885LMNA 4821/4885HTT 3829/4885 |
| US-20230002370-A1 | DERIVATIVES OF RESIQUIMOD | MYD88, TLR7, HLA-DRB1 | ALDH1A1 865/4885LMNA 4821/4885HTT 3829/4885 |
| US-11274099-B2 | Derivatives of Resiquimod | MYD88, TLR7, HLA-DRB1 | ALDH1A1 865/4885LMNA 4821/4885HTT 3829/4885 |
| US-12077535-B2 | Derivatives of resiquimod | MYD88, TLR7, HLA-DRB1 | ALDH1A1 865/4885LMNA 4821/4885HTT 3829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.