SCHEMBL20564435

SCHEMBL20564435

CCCC(/C=C/C(=O)O)=C(/CCC)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 0.39
TSHR P16473 3/20 0.38
TP53 P04637 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
EGLN3 Q9H6Z9 1/20 0.38
FFAR3 O14843 2/20 0.37
HDAC3 O15379 2/20 0.37
HDAC1 Q13547 2/20 0.37
HDAC2 Q92769 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
FNTA P49354 2/20 0.34
FNTB P49356 2/20 0.34
THRB P10828 1/20 0.34
PGGT1B P53609 1/20 0.34
ACHE P22303 1/20 0.34
BACE1 P56817 1/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20564568 0.84 FNTA (0.44) HCAR2TP53FNTAFNTBTHRB
Fumaric Acid SCHEMBL11403351 0.78 HCAR2 (0.38) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL3842599 0.74 TSHR (0.41) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL3842600 0.74 TSHR (0.41) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL554603 0.74 HDAC3 (0.56) TSHRFFAR3HDAC3HDAC1HDAC2
SCHEMBL554602 0.74 HDAC3 (0.56) TSHRFFAR3HDAC3HDAC1HDAC2
SCHEMBL184432 0.74 HDAC3 (0.56) TSHRFFAR3HDAC3HDAC1HDAC2
Fumaric Acid SCHEMBL28098613 0.72 FFAR3 (0.72) HCAR2TSHRTP53EGLN1EGLN3
Maleic Acid SCHEMBL28313754 0.72 FFAR3 (0.72) HCAR2TSHRTP53EGLN1EGLN3
Maleic Acid SCHEMBL6690087 0.72 TSHR (0.50) HCAR2TSHRTP53EGLN1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3625283-B1 POLYESTER COPOLYMER AVANTIUM KNOWLEDGE CENTRE BV (NL) 2025-05-07 EP disclosed
US-11548980-B2 Polyester copolymer AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2023-01-10 US disclosed
US-20210139645-A1 Polyester Copolymer AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2021-05-13 US disclosed
EP-3625283-A1 POLYESTER COPOLYMER Avantium Knowledge Centre B.V. (NL) 2020-03-25 EP disclosed
WO-2018211132-A1 POLYESTER COPOLYMER AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2018-11-22 WO disclosed