Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21868460 | 0.82 | RIPK1 (0.68) | RIPK1 | |
| SCHEMBL20565160 | 0.81 | RIPK1 (0.67) | RIPK1 | |
| SCHEMBL31111333 | 0.81 | RIPK1 (0.67) | RIPK1 | |
| SCHEMBL21867453 | 0.76 | RIPK1 (0.69) | RIPK1 | |
| SCHEMBL29385370 | 0.76 | RIPK1 (0.69) | RIPK1 | |
| SCHEMBL21867720 | 0.76 | RIPK1 (0.70) | RIPK1 | |
| SCHEMBL21868468 | 0.75 | RIPK1 (0.87) | RIPK1 | |
| Hydrochloric Acid SCHEMBL21800551 | 0.75 | RIPK1 (0.68) | RIPK1 | |
| SCHEMBL21868470 | 0.74 | RIPK1 (0.62) | RIPK1 | |
| SCHEMBL21868505 | 0.74 | RIPK1 (0.79) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3624797-A1 | KINASE INHIBITORS AND USES THEREOF | Denali Therapeutics Inc. (US) | 2020-03-25 | — | — | EP | disclosed |
| WO-2018213632-A1 | KINASE INHIBITORS AND USES THEREOF | DENALI THERAPEUTICS INC. (US) | 2018-11-22 | — | — | WO | disclosed |