SCHEMBL31111333

SCHEMBL31111333

COc1nc(N2CCC(OC)(C(=O)N3CCOc4c(C#N)cncc4C3)CC2)c(F)cc1F

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20565160 1.00 RIPK1 (0.67) RIPK1
SCHEMBL21867453 0.88 RIPK1 (0.69) RIPK1
SCHEMBL29385370 0.88 RIPK1 (0.69) RIPK1
SCHEMBL20564794 0.85 RIPK1 (0.61) RIPK1
SCHEMBL21868504 0.84 RIPK1 (0.84) RIPK1
SCHEMBL29383229 0.84 RIPK1 (0.84) RIPK1
SCHEMBL21867360 0.82 RIPK1 (0.81) RIPK1
SCHEMBL29382909 0.82 RIPK1 (0.81) RIPK1
SCHEMBL20565161 0.81 RIPK1 (0.54) RIPK1
SCHEMBL21867200 0.81 RIPK1 (0.68) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119285572-A Kinase inhibitors and uses thereof 戴纳立制药公司 2025-01-10 CN disclosed
CN-119264073-A Kinase inhibitors and uses thereof 戴纳立制药公司 2025-01-07 CN disclosed
CN-110913858-B Kinase inhibitors and uses thereof 戴纳立制药公司 2024-09-24 CN disclosed