Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.41 |
| ▸ | MMP12 | P39900 | 8/20 | 0.41 |
| ▸ | MMP13 | P45452 | 7/20 | 0.41 |
| ▸ | MMP14 | P50281 | 7/20 | 0.41 |
| ▸ | MMP9 | P14780 | 7/20 | 0.41 |
| ▸ | MMP8 | P22894 | 6/20 | 0.41 |
| ▸ | MMP16 | P51512 | 6/20 | 0.41 |
| ▸ | MMP1 | P03956 | 5/20 | 0.41 |
| ▸ | MMP3 | P08254 | 5/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749786 | 0.83 | CA1 (0.49) | MMP2MMP12MMP13MMP14MMP9 | |
| SCHEMBL18281576 | 0.83 | TTR (0.43) | MMP2MMP12MMP13MMP14MMP9 | |
| SCHEMBL5098746 | 0.83 | MMP2 (0.58) | MMP2MMP12MMP13MMP14MMP9 | |
| SCHEMBL2655044 | 0.81 | MEN1 (0.43) | MMP2MMP12MMP13MMP14MMP9 | |
| Hydrochloric Acid SCHEMBL6647677 | 0.80 | MEN1 (0.43) | MMP2MMP12MMP13MMP14MMP9 | |
| SCHEMBL28247232 | 0.80 | MMP2 (0.41) | MMP2MMP12MMP13MMP14MMP9 | |
| SCHEMBL6026006 | 0.79 | MAPK1 (0.46) | MMP2MMP12MMP13MMP14MMP9 | |
| SCHEMBL11324205 | 0.77 | PTGDR2 (0.45) | MMP2MMP12MMP13MMP14MMP9 | |
| SCHEMBL10339218 | 0.77 | AKR1B1 (0.46) | CA2PKMGAANPSR1PLA2G2A | |
| SCHEMBL27411189 | 0.76 | PNMT (0.46) | CA2CA1CA9GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10711121-B2 | Rubber composition and tire | BRIDGESTONE CORPORATION (JP) | 2020-07-14 | — | — | US | disclosed |
| US-20180355155-A1 | RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2018-12-13 | — | — | US | disclosed |
| EP-3406663-A1 | RUBBER COMPOSITION AND TIRE | Bridgestone Corporation (JP) | 2018-11-28 | — | — | EP | disclosed |