SCHEMBL20565978

SCHEMBL20565978

Clc1cccc(-c2nc(Cl)nc(-c3ccccc3)n2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1I3 Q14994 1/20 0.53
DPP4 P27487 1/20 0.53
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
TP53 P04637 1/20 0.49
TSHR P16473 1/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
L3MBTL1 Q9Y468 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
PDE5A O76074 3/20 0.48
ABCG2 Q9UNQ0 2/20 0.48
ABCB1 P08183 1/20 0.48
ABCC1 P33527 1/20 0.48
IDO1 P14902 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29664448 1.00 NR1I3 (0.53) NR1I3DPP4NPC1RAB9ASMN1; SMN2
SCHEMBL15477947 0.94 NR1I3 (0.57) NR1I3DPP4NPC1RAB9ASMN1; SMN2
SCHEMBL30476538 0.94 IDO1 (0.52) NR1I3DPP4NPC1RAB9ASMN1; SMN2
SCHEMBL17416252 0.94 IDO1 (0.52) NR1I3DPP4NPC1RAB9ASMN1; SMN2
SCHEMBL30035200 0.94 NR1I3 (0.57) NR1I3DPP4NPC1RAB9ASMN1; SMN2
SCHEMBL20150033 0.94 NR1I3 (0.57) NR1I3DPP4NPC1RAB9ASMN1; SMN2
SCHEMBL30986826 0.92 NR1I3 (0.55) NR1I3DPP4NPC1RAB9ASMN1; SMN2
SCHEMBL30986825 0.92 NR1I3 (0.55) NR1I3DPP4NPC1RAB9ASMN1; SMN2
SCHEMBL19007139 0.90 NR1I3 (0.54) NR1I3DPP4NPC1RAB9ASMN1; SMN2
SCHEMBL21689650 0.90 NR1I3 (0.54) NR1I3DPP4NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188031-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-06-12 US disclosed
US-12319653-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2025-06-03 US disclosed
EP-4531531-A1 ORGANIC LIGHT EMITTING DEVICE, DISPLAY DEVICE COMPRISING THE SAME AND COMPOUND Novaled GmbH (DE) 2025-04-02 EP disclosed
US-20240292743-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2024-08-29 US disclosed
CN-112135822-B N-heteroarylene compounds with low LUMO energy 诺瓦尔德股份有限公司 2024-07-16 CN disclosed
WO-2024144220-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 솔루스첨단소재 주식회사 2024-07-04 WO disclosed
WO-2024144213-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 솔루스첨단소재 주식회사 2024-07-04 WO disclosed
EP-3790875-B1 N-HETEROARYLENE COMPOUNDS WITH LOW LUMO ENERGIES NOVALED GMBH (DE) 2024-07-03 EP disclosed
EP-3790875-B1 N-HETEROARYLENE COMPOUNDS WITH LOW LUMO ENERGIES NOVALED GMBH (DE) 2024-07-03 EP disclosed
CN-118271294-A Organic electroluminescent material and device 环球展览公司 2024-07-02 CN disclosed
WO-2019216743-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE USING SAME 주식회사 엘지화학 (KR) 2019-11-14 WO disclosed
EP-3567039-A1 N-HETEROARYLENE COMPOUNDS WITH LOW LUMO ENERGIES Novaled GmbH (DE) 2019-11-13 EP disclosed
EP-3567039-A1 N-HETEROARYLENE COMPOUNDS WITH LOW LUMO ENERGIES Novaled GmbH (DE) 2019-11-13 EP disclosed
WO-2019078462-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2019-04-25 WO disclosed
WO-2019078461-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2019-04-25 WO disclosed
WO-2019078462-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2019-04-25 WO disclosed
WO-2019072932-A1 ORGANIC ELECTRONIC DEVICE COMPRISING AN ORGANIC SEMICONDUCTOR LAYER NOVALED GMBH (DE) 2019-04-18 WO disclosed
EP-3470398-A1 ORGANIC ELECTRONIC DEVICE COMPRISING AN ORGANIC SEMICONDUCTOR LAYER Novaled GmbH (DE) 2019-04-17 EP disclosed
EP-3470398-A1 ORGANIC ELECTRONIC DEVICE COMPRISING AN ORGANIC SEMICONDUCTOR LAYER Novaled GmbH (DE) 2019-04-17 EP disclosed
EP-3407401-A1 ORGANIC ELECTRONIC DEVICE COMPRISING AN ORGANIC SEMICONDUCTOR LAYER AND A DEVICE Novaled GmbH (DE) 2018-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188031-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PIEZO1, OR10J3, ETV6 NR1I3 4456/4885DPP4 4446/4885NPC1 2910/4885
US-12319653-B2 Organic electroluminescent materials and devices PIEZO1, OR10J3, LEF1 NR1I3 4378/4885DPP4 4389/4885NPC1 2575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.