SCHEMBL2056622

SCHEMBL2056622

NC(O)[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)C[C@@H]1O

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DUT P33316 4/20 0.51
SLC28A1 O00337 1/20 0.43
SLC28A2 O43868 1/20 0.43
SLC29A1 Q99808 1/20 0.43
SLC28A3 Q9HAS3 1/20 0.43
P2RY2 P41231 5/20 0.39
P2RY6 Q15077 3/20 0.39
P2RY4 P51582 3/20 0.39
TK1 P04183 2/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6034458 0.92 DUT (0.53) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL1619707 0.90 DUT (0.49) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL1619710 0.90 DUT (0.49) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL414704 0.90 DUT (0.51) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL10765602 0.90 DUT (0.51) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL249821 0.90 DUT (0.51) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL15771583 0.90 DUT (0.51) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL28745696 0.90 DUT (0.51) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL3340603 0.88 DUT (0.50) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL51722 0.88 DUT (0.53) DUTSLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117512038-A Sansansamycin derivatives and application thereof 中国医学科学院医药生物技术研究所 2024-02-06 CN claimed
CN-117512038-A Sansansamycin derivatives and application thereof 中国医学科学院医药生物技术研究所 2024-02-06 CN disclosed
US-20110104754-A1 CELL CULTURE MEDIUM GENETIX LIMITED 2011-05-05 US disclosed
EP-1818392-B1 Cell culture medium GENETIX LTD (GB) 2010-08-25 EP disclosed
US-20070212778-A1 Cell culture medium GENETIX LIMITED 2007-09-13 US disclosed
EP-1818392-A1 Cell culture medium Genetix Limited (GB) 2007-08-15 EP disclosed
US-5213972-A Production of thymidine and deoxyuridine, intermediates for AZT CHEMGEN CORPORATION (US) 1993-05-25 US disclosed