SCHEMBL414704

SCHEMBL414704

O=c1ccn([C@H]2C[C@H](O)[C@@H](C(O)Cl)O2)c(=O)[nH]1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DUT P33316 4/20 0.51
SLC28A1 O00337 1/20 0.43
SLC28A2 O43868 1/20 0.43
SLC29A1 Q99808 1/20 0.43
SLC28A3 Q9HAS3 1/20 0.43
P2RY2 P41231 5/20 0.39
P2RY6 Q15077 3/20 0.39
TK1 P04183 3/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
P2RY4 P51582 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15771583 1.00 DUT (0.51) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL6034458 0.92 DUT (0.53) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL10765602 0.90 DUT (0.51) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL2056622 0.90 DUT (0.51) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL249821 0.90 DUT (0.51) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL28745696 0.90 DUT (0.51) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL51722 0.88 DUT (0.53) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL3340603 0.88 DUT (0.50) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL41471 0.88 DUT (0.50) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL4954183 0.88 DUT (0.53) DUTSLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200385789-A1 METHODS OF ASSESSING TELOMERES CHILDREN'S MEDICAL RESEARCH INSTITUTE (AU) 2020-12-10 US claimed
EP-3676609-A1 METHODS OF ASSESSING TELOMERES Children's Medical Research Institute (AU) 2020-07-08 EP claimed
WO-2019040993-A1 METHODS OF ASSESSING TELOMERES CHILDREN'S MEDICAL RESEARCH INSTITUTE (AU) 2019-03-07 WO claimed
US-9644238-B2 Methods of isolating non-senescent cardiac stem cells and uses thereof AUTOLOGOUS REGENERATION, LLC (US) 2017-05-09 US claimed
US-20170022242-A1 NOVEL ANTIVIRAL AND ANTITUMORAL COMPOUNDS Katholieke Universiteit Leuven, KU LEUVEN R&D (BE) 2017-01-26 US claimed
WO-2015158913-A1 NOVEL ANTIVIRAL AND ANTITUMORAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2015-10-22 WO claimed
US-20140051077-A1 METHODS OF ISOLATING NON-SENESCENT CARDIAC STEM CELLS AND USES THEREOF AUTOLOGOUS, LLC (US) 2014-02-20 US claimed
EP-2635292-A1 METHODS OF ISOLATING NON-SENESCENT CARDIAC STEM CELLS AND USES THEREOF Autologous, LLC (US) 2013-09-11 EP claimed
US-8512696-B2 Methods of isolating non-senescent cardiac stem cells and uses thereof AUTOLOGOUS, LLC (US) 2013-08-20 US claimed
WO-2012061491-A1 METHODS OF ISOLATING NON-SENESCENT CARDIAC STEM CELLS AND USES THEREOF ANVERSA PIERO (US) 2012-05-10 WO claimed
US-7635467-B2 Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-12-22 US claimed
US-7618621-B2 Mammalian multipotent neural stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-11-17 US claimed
US-20030229004-A1 Modulation of tumor cells using BER inhibitors in combination with a sensitizing agent and DSBR inhibitors PANGENE CORPORATION 2003-12-11 US claimed
WO-1996025147-A1 LIPOSOME COMPOSITION AND METHOD FOR ADMINISTERING LIPOSOME-LOADABLE DRUGS SEQUUS PHARMACEUTICALS, INC. (US) 1996-08-22 WO claimed
WO-1996021665-A1 TURCASARINS, NOVEL EXPANDED PORPHYRINS, AND USES THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1996-07-18 WO claimed
US-4780406-A Flow cytometric measurement of total DNA and incorporated halodeoxyuridine THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1988-10-25 US claimed
US-4585736-A Flow cytometric measurement of total DNA and incorporated halodeoxyuridine THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1986-04-29 US claimed
US-20250207177-A1 METHODS, COMPOSITIONS AND DEVICES FOR SPREADING OF CHROMATIN FIBERS ERASMUS UNIVERSITY MEDICAL CENTER (NL) 2025-06-26 US disclosed
WO-1996013552-A2 SUBSTITUTED UNSYMMETRICAL CYANINE DYES WITH SELECTED PERMEABILITY MOLECULAR PROBES, INC. (US) 1996-05-09 WO disclosed
US-5213972-A Production of thymidine and deoxyuridine, intermediates for AZT CHEMGEN CORPORATION (US) 1993-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170022242-A1 NOVEL ANTIVIRAL AND ANTITUMORAL COMPOUNDS PNP, NTPCR, ENTPD5 DUT 45/4885SLC28A1 41/4885SLC28A2 57/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.