Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 8/20 | 0.37 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | TEC | P42680 | 2/20 | 0.32 |
| ▸ | TXK | P42681 | 2/20 | 0.32 |
| ▸ | ITK | Q08881 | 2/20 | 0.32 |
| ▸ | BMX | P51813 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439865 | 1.00 | BTK (0.37) | BTKUBE2MDCUN1D1SLC6A9SLC6A5 | |
| SCHEMBL9932890 | 0.88 | STS (0.37) | BTKUBE2MDCUN1D1 | |
| SCHEMBL1439999 | 0.83 | GRM4 (0.39) | BTKUBE2MDCUN1D1SLC6A9SLC6A5 | |
| SCHEMBL1440003 | 0.83 | GRM4 (0.39) | BTKUBE2MDCUN1D1SLC6A9SLC6A5 | |
| SCHEMBL22818580 | 0.83 | BTK (0.35) | BTKUBE2MDCUN1D1SLC6A9SLC6A5 | |
| SCHEMBL20566873 | 0.72 | TGM2 (0.43) | CCR5 | |
| SCHEMBL1440097 | 0.72 | TGM2 (0.43) | CCR5 | |
| SCHEMBL1439945 | 0.72 | TGM2 (0.43) | CCR5 | |
| SCHEMBL1439320 | 0.72 | GRM4 (0.39) | GRM4 | |
| SCHEMBL1439322 | 0.72 | GRM4 (0.39) | GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473049-B1 | BRUTON'S TYROSINE KINASE INHIBITORS | BIOGEN MA INC (US) | 2018-11-28 | — | — | EP | disclosed |