Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 8/20 | 0.43 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | TGM1 | P22735 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 7/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439945 | 1.00 | TGM2 (0.43) | TGM2F13A1TGM1CTSKCTSL | |
| SCHEMBL1440097 | 1.00 | TGM2 (0.43) | TGM2F13A1TGM1CTSKCTSL | |
| SCHEMBL9933255 | 0.90 | ITGB3 (0.43) | CTSKCTSLCTSSITGB3ITGA2B | |
| SCHEMBL9933258 | 0.90 | ITGB3 (0.43) | CTSKCTSLCTSSITGB3ITGA2B | |
| SCHEMBL28442161 | 0.90 | ITGB3 (0.43) | CTSKCTSLCTSSITGB3ITGA2B | |
| SCHEMBL9934458 | 0.90 | ITGB3 (0.43) | CTSKCTSLCTSSITGB3ITGA2B | |
| SCHEMBL13923719 | 0.72 | ACE (0.63) | ACEPREP | |
| SCHEMBL20566871 | 0.72 | BTK (0.37) | CCR5 | |
| SCHEMBL12877486 | 0.72 | PREP (0.50) | TGM2F13A1TGM1CTSKCTSL | |
| SCHEMBL23295571 | 0.71 | CTSK (0.54) | CTSKCTSLCTSSCTSBACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473049-B1 | BRUTON'S TYROSINE KINASE INHIBITORS | BIOGEN MA INC (US) | 2018-11-28 | — | — | EP | disclosed |