SCHEMBL20567405

SCHEMBL20567405

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nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28326673 0.90 THRB (0.30) ALDH1A1
SCHEMBL14686168 0.90 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL6575777 0.89 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL17801655 0.89 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL25561 0.89 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL1512952 0.88 ALDH1A1 (0.39) ALDH1A1TSHR
Methyl Alcohol SCHEMBL28203244 0.88 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL3896816 0.87
Acrylic Acid SCHEMBL28111560 0.87 ALDH1A1 (0.33) ALDH1A1TSHR
Alcohol SCHEMBL23859971 0.86 ALDH1A1 (0.38) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10576307-B2 Hair-treatment compositions, methods, and kits for treating hair L'OREAL (FR) 2020-03-03 US disclosed
US-10561599-B2 Methods and kits for treating chemically relaxed hair L'OREAL (FR) 2020-02-18 US disclosed
WO-2018218007-A1 METHODS AND KITS FOR TREATING CHEMICALLY RELAXED HAIR L'OREAL (FR) 2018-11-29 WO disclosed
US-20180339175-A1 HAIR-TREATMENT COMPOSITIONS, METHODS, AND KITS FOR TREATING HAIR L'OREAL (FR) 2018-11-29 US disclosed
US-20180338901-A1 METHODS AND KITS FOR TREATING CHEMICALLY RELAXED HAIR L'OREAL (FR) 2018-11-29 US disclosed
WO-2018218009-A2 HAIR-TREATMENT COMPOSITIONS, METHODS, AND KITS FOR TREATNG HAIR L'OREAL (FR) 2018-11-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10576307-B2 Hair-treatment compositions, methods, and kits for treating hair OTC, TET3, SUCLG1 ALDH1A1 295/4885TSHR 1885/4885
US-10561599-B2 Methods and kits for treating chemically relaxed hair CRAT, DNMT1, TET3 ALDH1A1 526/4885TSHR 852/4885
US-20180339175-A1 HAIR-TREATMENT COMPOSITIONS, METHODS, AND KITS FOR TREATING HAIR OTC, TET3, SUCLG1 ALDH1A1 295/4885TSHR 1885/4885
US-20180338901-A1 METHODS AND KITS FOR TREATING CHEMICALLY RELAXED HAIR CRAT, DNMT1, TET3 ALDH1A1 526/4885TSHR 852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.