SCHEMBL20567466

SCHEMBL20567466

O=C(CBr)NCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCc1nnn[nH]1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.50
▸ GLO1 Q04760 1/20 0.38
▸ CCKAR P32238 7/20 0.35
▸ CCKBR P32239 7/20 0.35
▸ FOLH1 Q04609 2/20 0.35
▸ NOD1 Q9Y239 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20567468 1.00 GLP1R (0.50) GLP1RGLO1CCKARCCKBRFOLH1
SCHEMBL28400630 1.00 GLP1R (0.50) GLP1RGLO1CCKARCCKBRFOLH1
SCHEMBL28400628 1.00 GLP1R (0.50) GLP1RGLO1CCKARCCKBRFOLH1
SCHEMBL16809355 0.92 GLP1R (0.50) GLP1RGLO1FOLH1NOD1
SCHEMBL12673959 0.91 GLP1R (0.53) GLP1RGLO1CCKARCCKBRFOLH1
SCHEMBL12673965 0.91 GLP1R (0.53) GLP1RGLO1CCKARCCKBRFOLH1
SCHEMBL12673961 0.91 GLP1R (0.53) GLP1RGLO1CCKARCCKBRFOLH1
SCHEMBL19243827 0.91 GLP1R (0.53) GLP1RGLO1CCKARCCKBRFOLH1
SCHEMBL15824613 0.90 GLP1R (0.50) GLP1RGLO1CCKARCCKBRFOLH1
SCHEMBL13025471 0.89 GLP1R (0.53) GLP1RGLO1CCKARCCKBRNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230364248-A1 MIC-1 COMPOUNDS AND USES THEREOF NOVO NORDISK AS (DK) 2023-11-16 — — US disclosed
US-20230364248-A1 MIC-1 COMPOUNDS AND USES THEREOF NOVO NORDISK AS (DK) 2023-11-16 — — US disclosed
US-20200079829-A1 MIC-1 COMPOUNDS AND USES THEREOF NOVO NORDISK A/S (DK) 2020-03-12 — — US disclosed
US-10398782-B2 MIC-1 compounds and uses thereof NOVO NORDISK A/S (DK) 2019-09-03 — — US disclosed
US-10398782-B2 MIC-1 compounds and uses thereof NOVO NORDISK A/S (DK) 2019-09-03 — — US disclosed
US-20180339057-A1 MIC-1 Compounds and Uses Thereof NOVO NORDISK A/S (DK) 2018-11-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200079829-A1 MIC-1 COMPOUNDS AND USES THEREOF IMMT, MICA, TAP1 GLP1R 710/4885GLO1 1557/4885CCKAR 1112/4885
US-10398782-B2 MIC-1 compounds and uses thereof IMMT, MICA, TAP1 GLP1R 710/4885GLO1 1557/4885CCKAR 1112/4885
US-20230364248-A1 MIC-1 COMPOUNDS AND USES THEREOF IMMT, MICA, TAP1 GLP1R 710/4885GLO1 1557/4885CCKAR 1112/4885
US-20180339057-A1 MIC-1 Compounds and Uses Thereof IMMT, MICA, TAP1 GLP1R 710/4885GLO1 1557/4885CCKAR 1112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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