Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14569541 | 0.81 | IDO1 (0.47) | IDO1ALDH1A1LMNA | |
| SCHEMBL4520546 | 0.79 | TSHR (0.53) | CYP3A4TSHRTDP1MAPK1L3MBTL1 | |
| SCHEMBL26017464 | 0.79 | L3MBTL1 (0.38) | CYP3A4TSHRTDP1MAPK1L3MBTL1 | |
| SCHEMBL25077871 | 0.79 | CYP3A4 (0.45) | CYP3A4TSHRTDP1MAPK1P2RX1 | |
| SCHEMBL20568864 | 0.78 | L3MBTL1 (0.43) | CYP3A4L3MBTL1P2RX1CETPPIN1 | |
| SCHEMBL25771219 | 0.77 | L3MBTL1 (0.37) | CYP3A4TSHRTDP1MAPK1L3MBTL1 | |
| SCHEMBL4975333 | 0.76 | IDO1 (0.43) | CYP3A4TSHRTDP1MAPK1P2RX1 | |
| SCHEMBL14493293 | 0.75 | CYP3A4 (0.43) | CYP3A4TSHRTDP1MAPK1L3MBTL1 | |
| SCHEMBL131155 | 0.75 | ALDH1A1 (0.43) | CYP3A4TSHRTDP1MAPK1L3MBTL1 | |
| SCHEMBL15542723 | 0.75 | ALDH1A1 (0.43) | CYP3A4TSHRTDP1MAPK1P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601752-A | Novel inhibitors of MAP4K1 | 伊克诺斯科学公司 | 2021-04-02 | — | — | CN | disclosed |
| EP-3630778-A1 | NOVEL INHIBITORS OF MAP4K1 | Ichnos Sciences SA (CH) | 2020-04-08 | — | — | EP | disclosed |
| WO-2018215668-A1 | NOVEL INHIBITORS OF MAP4K1 | GLENMARK PHARMACEUTICALS S.A. (CH) | 2018-11-29 | — | — | WO | disclosed |