Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPO | P22079 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20569871 | 0.71 | BCHE (0.39) | LPO | |
| SCHEMBL14002933 | 0.63 | LPO (0.48) | LPO | |
| SCHEMBL20569372 | 0.62 | CYP1A2 (0.39) | — | |
| SCHEMBL30109124 | 0.59 | NOTUM (0.39) | LPO | |
| SCHEMBL4167876 | 0.59 | NOTUM (0.39) | LPO | |
| SCHEMBL14630050 | 0.58 | PARP1 (0.42) | LPO | |
| SCHEMBL29559884 | 0.58 | PARP1 (0.42) | LPO | |
| SCHEMBL20568595 | 0.56 | BCHE (0.40) | LPO | |
| SCHEMBL29083460 | 0.56 | CYP3A4 (0.40) | LPO | |
| SCHEMBL423280 | 0.56 | KDM4E (0.42) | LPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630728-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | Oxford University Innovation Limited (GB) | 2020-04-08 | — | — | EP | disclosed |
| WO-2018215799-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2018-11-29 | — | — | WO | disclosed |