Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.43 |
| ▸ | BRAF | P15056 | 5/20 | 0.37 |
| ▸ | CCR2 | P41597 | 6/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12398713 | 0.82 | TACR1 (0.43) | TACR1BRAFABL1MCHR1 | |
| SCHEMBL10104262 | 0.76 | NOS1 (0.45) | TACR1BRAFABL1MCHR1 | |
| SCHEMBL2201726 | 0.75 | NOS1 (0.39) | TACR1BRAFABL1 | |
| SCHEMBL15131546 | 0.74 | TEK (0.44) | TACR1CCR2 | |
| SCHEMBL24781287 | 0.74 | NOS1 (0.41) | TACR1CCR2 | |
| Hydrochloric Acid SCHEMBL15122987 | 0.73 | TEK (0.43) | TACR1CCR2 | |
| SCHEMBL13130561 | 0.73 | TACR1 (0.39) | TACR1BRAFCCR2 | |
| SCHEMBL18794873 | 0.71 | TACR1 (0.52) | TACR1 | |
| SCHEMBL20568892 | 0.71 | NOTUM (0.46) | TACR1 | |
| SCHEMBL15397669 | 0.69 | TACR1 (0.59) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630778-A1 | NOVEL INHIBITORS OF MAP4K1 | Ichnos Sciences SA (CH) | 2020-04-08 | — | — | EP | disclosed |
| WO-2018215668-A1 | NOVEL INHIBITORS OF MAP4K1 | GLENMARK PHARMACEUTICALS S.A. (CH) | 2018-11-29 | — | — | WO | disclosed |