SCHEMBL20568989

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20568331	0.91	RXRA (0.45)	RPA1MCL1CES1KDM4EALDH1A1
	SCHEMBL29750742	0.91	RXRA (0.45)	RPA1MCL1CES1KDM4EALDH1A1
	SCHEMBL20568215	0.79	RPA1 (0.41)	RPA1MCL1KDM4EALDH1A1HPGD
	SCHEMBL20570013	0.76	KDM4E (0.52)	RPA1MCL1KDM4EALDH1A1HPGD
	SCHEMBL29750702	0.76	CES1 (0.46)	CES1HTTACHEHDAC1HDAC6
	SCHEMBL20568605	0.73	ESR1 (0.49)	RPA1MCL1KDM4EALDH1A1HPGD
	SCHEMBL20568349	0.72	RPA1 (0.47)	RPA1MCL1KDM4EALDH1A1HPGD
	SCHEMBL20568071	0.72	MAP2 (0.49)	RPA1MCL1KDM4EALDH1A1HPGD
	SCHEMBL23327330	0.72	GPR35 (0.38)	RPA1MCL1KDM4EALDH1A1HPGD
	SCHEMBL29750732	0.72	GPR35 (0.38)	RPA1MCL1KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.