Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26127200 | 0.80 | LMNA (0.54) | KMT2ALMNA | |
| SCHEMBL20570136 | 0.78 | TSHR (0.53) | TDP1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL20570065 | 0.77 | CYP1A2 (0.48) | TDP1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL20570489 | 0.76 | TDP1 (0.47) | TDP1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL26123954 | 0.76 | KCNH2 (0.41) | CYP1A2CYP2C19LMNA | |
| SCHEMBL20569452 | 0.75 | GRM2 (0.40) | TDP1KMT2ACYP1A2CYP2D6CYP2C19 | |
| Iodide SCHEMBL29037976 | 0.75 | TDP1 (0.61) | TDP1KMT2ACYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL28192676 | 0.75 | TDP1 (0.61) | TDP1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8359430 | 0.74 | CYP19A1 (0.47) | LMNA | |
| SCHEMBL20569547 | 0.72 | ADRA2C (0.58) | TDP1CYP1A2CYP2D6CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |