Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20570153 | 0.86 | FLT1 (0.40) | KCNH2FLT1KDRLMNASMN1; SMN2 | |
| SCHEMBL20570755 | 0.83 | FLT1 (0.39) | KCNH2FLT1KDRLMNASMN1; SMN2 | |
| SCHEMBL20570753 | 0.83 | FLT1 (0.39) | KCNH2FLT1KDRLMNASMN1; SMN2 | |
| SCHEMBL20569538 | 0.82 | ABCB11 (0.41) | CYP3A4FLT1KDRLMNASMN1; SMN2 | |
| SCHEMBL20570323 | 0.76 | KCNH2 (0.49) | KCNH2ALDH1A1CYP3A4FLT1KDR | |
| SCHEMBL20569455 | 0.76 | KCNH2 (0.49) | KCNH2BRD4 | |
| SCHEMBL20569454 | 0.76 | KCNH2 (0.40) | KCNH2SMN1; SMN2 | |
| SCHEMBL20569246 | 0.76 | TLR8 (0.53) | KCNH2ALDH1A1CYP3A4FLT1KDR | |
| SCHEMBL20572275 | 0.75 | KCNH2 (0.50) | KCNH2SMN1; SMN2CYP2D6CYP2C19 | |
| SCHEMBL4910247 | 0.75 | KMT2A (0.44) | KCNH2ALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |