Sugi Predict

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SCHEMBL20569208

SCHEMBL20569208

CC1=C(C)C(C)(COC(=O)CCC(=O)O)C(C)=C1C

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ CYP2C19 P33261 1/20 0.37
▸ EGLN1 Q9GZT9 2/20 0.37
▸ KDM6B O15054 1/20 0.37
▸ KDM5C P41229 1/20 0.37
▸ PHF8 Q9UPP1 1/20 0.37
▸ KDM2A Q9Y2K7 1/20 0.37
▸ LMNA P02545 3/20 0.35
▸ ALKBH5 Q6P6C2 1/20 0.32
▸ SUCNR1 Q9BXA5 1/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ PKM P14618 1/20 0.32
▸ SLC15A2 Q16348 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ TSHR P16473 2/20 0.31
▸ ADRA2A P08913 1/20 0.31
▸ ADRA1A P35348 1/20 0.31
▸ PAM P19021 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20569206 0.93 ADRA2A (0.34) SMN1; SMN2TSHRADRA2AADRA1A
SCHEMBL25815979 0.84 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL26309959 0.82 CYP1A2 (0.40) TSHR
SCHEMBL25814226 0.79 ALDH1A1 (0.36) CYP2C19LMNAALDH1A1KMT2ATSHR
SCHEMBL22184135 0.79 CYP1A2 (0.31) —
SCHEMBL22184148 0.78 TSHR (0.32) TSHR
SCHEMBL22184147 0.76 — —
SCHEMBL26309164 0.76 KDM6B (0.31) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL22184086 0.76 PSMB8 (0.31) TSHR
SCHEMBL26293409 0.75 TSHR (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250152728-A1 Method And Molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-05-15 — — US disclosed
US-20230321267-A1 Method And Molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-10-12 — — US disclosed
US-11759526-B2 Method and molecules MEDIMMUNE, LLC (US) 2023-09-19 — — US disclosed
EP-4223319-A2 METHOD AND MOLECULES MedImmune, LLC (US) 2023-08-09 — — EP disclosed
EP-3630732-B1 METHOD AND MOLECULES MEDIMMUNE LLC (US) 2023-07-12 — — EP disclosed
CN-110650947-B Methods and molecules 免疫医疗有限责任公司 2023-05-12 — — CN disclosed
US-20200206359-A1 Method And Molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-07-02 — — US disclosed
EP-3630732-A1 METHOD AND MOLECULES Medimmune, LLC (US) 2020-04-08 — — EP disclosed
CN-110650947-A Methods and molecules 免疫医疗有限责任公司 2020-01-03 — — CN disclosed
WO-2018218093-A1 METHOD AND MOLECULES MEDIMMUNE, LLC (US) 2018-11-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250152728-A1 Method And Molecules PAICS, EPCAM, SQLE CYP2C19 1042/4885EGLN1 2128/4885KDM6B 3281/4885
US-20200206359-A1 Method And Molecules PAICS, EPCAM, SQLE CYP2C19 1042/4885EGLN1 2128/4885KDM6B 3281/4885
US-20230321267-A1 Method And Molecules PAICS, EPCAM, SQLE CYP2C19 1042/4885EGLN1 2128/4885KDM6B 3281/4885
US-11759526-B2 Method and molecules PAICS, EPCAM, SQLE CYP2C19 1042/4885EGLN1 2128/4885KDM6B 3281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.