Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20570528 | 0.88 | FFAR1 (0.42) | — | |
| SCHEMBL6582299 | 0.87 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNA | |
| SCHEMBL20569098 | 0.86 | FPR2 (0.45) | — | |
| SCHEMBL20569454 | 0.86 | KCNH2 (0.40) | SMN1; SMN2 | |
| SCHEMBL26041570 | 0.84 | SMN1; SMN2 (0.51) | TDP1SMN1; SMN2 | |
| SCHEMBL20569190 | 0.83 | SMN1; SMN2 (0.42) | TDP1SMN1; SMN2 | |
| SCHEMBL20570534 | 0.82 | KCNH2 (0.39) | SMN1; SMN2 | |
| Iodide SCHEMBL29037976 | 0.81 | TDP1 (0.61) | TDP1CYP1A2CYP2D6CYP2C19LMNA | |
| Hydrochloric Acid SCHEMBL28192676 | 0.81 | TDP1 (0.61) | TDP1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL27721562 | 0.79 | KMT2A (0.56) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |