Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20569454 | 0.96 | KCNH2 (0.40) | KCNH2FPR2SMN1; SMN2 | |
| SCHEMBL20572275 | 0.85 | KCNH2 (0.50) | KCNH2SMN1; SMN2 | |
| SCHEMBL6582299 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2 | |
| SCHEMBL20569140 | 0.83 | FLT1 (0.37) | FLT1KDR | |
| SCHEMBL20569098 | 0.83 | FPR2 (0.45) | FPR2 | |
| SCHEMBL20570174 | 0.83 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL20569838 | 0.83 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL20569447 | 0.82 | TDP1 (0.45) | SMN1; SMN2 | |
| SCHEMBL20570528 | 0.82 | FFAR1 (0.42) | — | |
| SCHEMBL20571221 | 0.82 | FLT1 (0.38) | FLT1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |