Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2221149 | 0.76 | TSHR (0.50) | CYP2C19MEN1KMT2ATSHRSLC6A2 | |
| SCHEMBL11892291 | 0.71 | ALDH1A1 (0.49) | CYP2C19MEN1KMT2ATSHRSLC6A2 | |
| SCHEMBL14413593 | 0.71 | ALDH1A1 (0.49) | CYP2C19MEN1KMT2ATSHRSLC6A2 | |
| SCHEMBL751413 | 0.71 | ALDH1A1 (0.49) | CYP2C19MEN1KMT2ATSHRSLC6A2 | |
| SCHEMBL27460712 | 0.65 | CYP19A1 (0.39) | MEN1KMT2ATSHRSLC6A2SLC6A3 | |
| SCHEMBL6244517 | 0.65 | TSHR (0.48) | CYP2C19MEN1KMT2ATSHRSLC6A2 | |
| SCHEMBL13897184 | 0.65 | TSHR (0.48) | CYP2C19MEN1KMT2ATSHRSLC6A2 | |
| SCHEMBL12539970 | 0.64 | CYP2A6 (0.42) | CYP2C19MEN1KMT2ATSHRSLC6A2 | |
| SCHEMBL733501 | 0.62 | CYP2C19 (0.58) | CYP2C19MEN1KMT2ATSHRSLC6A2 | |
| SCHEMBL366283 | 0.62 | CYP2C19 (0.62) | CYP2C19MEN1KMT2ATSHRSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |