Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20572275 | 0.89 | KCNH2 (0.50) | KCNH2NMT1 | |
| SCHEMBL20570174 | 0.86 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL20569454 | 0.86 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL20570534 | 0.83 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL20569140 | 0.82 | FLT1 (0.37) | — | |
| SCHEMBL20571350 | 0.81 | FLT1 (0.37) | — | |
| SCHEMBL20571221 | 0.80 | FLT1 (0.38) | — | |
| SCHEMBL20569070 | 0.78 | FLT1 (0.41) | — | |
| SCHEMBL20569455 | 0.76 | KCNH2 (0.49) | KCNH2NMT1BRD4 | |
| SCHEMBL20569246 | 0.76 | TLR8 (0.53) | KCNH2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |