Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.39 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20569180 | 0.83 | CHRM2 (0.38) | HRH3ESR1 | |
| SCHEMBL20568965 | 0.83 | DUT (0.37) | DUTHRH3MAOB | |
| SCHEMBL29001700 | 0.74 | ESR1 (0.45) | ESR1 | |
| SCHEMBL20568979 | 0.74 | APP (0.41) | DUT | |
| SCHEMBL18170322 | 0.74 | ESR1 (0.49) | HRH3ESR1 | |
| SCHEMBL31621061 | 0.70 | APP (0.42) | DUT | |
| SCHEMBL16291964 | 0.69 | HRH3 (0.41) | HRH3 | |
| SCHEMBL21831386 | 0.68 | DUT (0.34) | DUT | |
| SCHEMBL14862790 | 0.68 | CHRM3 (0.37) | HRH3 | |
| SCHEMBL23474991 | 0.67 | HRH3 (0.50) | HRH3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |