Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20569858 | 0.83 | DUT (0.40) | DUTHRH3MAOB | |
| SCHEMBL3019363 | 0.70 | ACACB (0.47) | HRH3ACACB | |
| SCHEMBL19297787 | 0.68 | PREP (0.42) | — | |
| SCHEMBL27038805 | 0.68 | ACACB (0.42) | ACACB | |
| SCHEMBL20569180 | 0.68 | CHRM2 (0.38) | HRH3 | |
| SCHEMBL25015315 | 0.67 | DUT (0.32) | DUT | |
| SCHEMBL13302936 | 0.66 | DUT (0.31) | DUT | |
| SCHEMBL3008315 | 0.66 | GABRA1 (0.30) | HRH3 | |
| SCHEMBL15062766 | 0.64 | — | — | |
| SCHEMBL29080221 | 0.64 | ACACB (0.34) | HRH3ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |