Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19926316 | 0.75 | MAPK1 (0.33) | KDM5A | |
| SCHEMBL710186 | 0.73 | KDM5A (0.48) | ADAKDM4EKDM5A | |
| SCHEMBL29663447 | 0.72 | ADA (0.47) | ADAKDM4EKDM5A | |
| SCHEMBL29663112 | 0.72 | ADA (0.47) | ADAKDM4EKDM5A | |
| SCHEMBL18040235 | 0.72 | ADA (0.47) | ADAKDM4EKDM5A | |
| Hydrochloric Acid SCHEMBL29910419 | 0.72 | KDM5A (0.47) | ADAKDM4EKDM5A | |
| SCHEMBL27894407 | 0.72 | KDM5A (0.47) | ADAKDM4EKDM5A | |
| SCHEMBL5092069 | 0.71 | PLA2G4A (0.38) | KDM4E | |
| SCHEMBL29215817 | 0.71 | KDM5A (0.46) | ADAKDM4EKDM5A | |
| SCHEMBL29215894 | 0.71 | KDM5A (0.46) | ADAKDM4EKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |