Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777002 | 0.84 | TSHR (0.59) | TSHRPTPN1CA1CA2CA9 | |
| SCHEMBL20798281 | 0.78 | ALDH1A1 (0.50) | TSHRALDH1A1PPARGPPARA | |
| SCHEMBL1521052 | 0.77 | TP53 (0.56) | TSHRALDH1A1IDO1FOLH1 | |
| SCHEMBL11294507 | 0.76 | TSHR (0.54) | TSHRPTPN1CA1CA2CA9 | |
| SCHEMBL27488099 | 0.76 | ALDH1A1 (0.54) | TSHRPTPN1CA1CA2CA9 | |
| SCHEMBL23003 | 0.76 | TSHR (0.79) | TSHRPTPN1CA1CA2CA9 | |
| SCHEMBL2057023 | 0.76 | PTPN1 (0.51) | TSHRPTPN1CA1CA2CA9 | |
| SCHEMBL3361331 | 0.76 | TSHR (0.57) | TSHRPTPN1CA1CA2CA9 | |
| SCHEMBL28370887 | 0.75 | TSHR (0.76) | TSHRPTPN1CA1CA2CA9 | |
| Ammonia Solution, Strong SCHEMBL27527756 | 0.75 | TSHR (0.76) | TSHRPTPN1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893253-B2 | Aminating reducing sugar; mass spectrometry | MERCK PATENT GMBH (DE) | 2011-02-22 | — | — | US | disclosed |
| EP-1846765-B1 | SOLID-PHASE OLIGOSACCHARIDE TAGGING: A TECHNIQUE FOR MANIPULATION OF IMMOBILIZED CARBOHYDRATES | MERCK PATENT GMBH (DE) | 2009-05-27 | — | — | EP | disclosed |
| US-20080227092-A1 | Solid-Phase Oligosaccharide Tagging: a Technique for Manipulation of Immobilized Carbohydrates | MERCK PATENT GESELLSCHAFT (DE) | 2008-09-18 | — | — | US | disclosed |
| EP-1846765-A1 | SOLID-PHASE OLIGOSACCHARIDE TAGGING: A TECHNIQUE FOR MANIPULATION OF IMMOBILIZED CARBOHYDRATES | Carlsberg A/S (DK) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006084461-A1 | SOLID-PHASE OLIGOSACCHARIDE TAGGING: A TECHNIQUE FOR MANIPULATION OF IMMOBILIZED CARBOHYDRATES | MERCK PATENT GMBH (DE) | 2006-08-17 | — | — | WO | disclosed |