Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | HNF4A | P41235 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23003 | 0.98 | TSHR (0.79) | TSHRFOLH1CA1CA2CA9 | |
| SCHEMBL28370887 | 0.96 | TSHR (0.76) | TSHRFOLH1CA1CA2CA9 | |
| Acetic Acid SCHEMBL28245857 | 0.92 | TSHR (0.71) | TSHRFOLH1CA1CA2CA9 | |
| Ethylene Glycol SCHEMBL1817402 | 0.92 | TSHR (0.71) | TSHRFOLH1CA1CA2CA9 | |
| Benzoic Acid SCHEMBL29974267 | 0.90 | TSHR (0.86) | TSHRFOLH1CA1CA2CA9 | |
| Benzyl Alcohol SCHEMBL5488535 | 0.90 | TSHR (0.69) | TSHRFOLH1CA1CA2CA9 | |
| Lindane SCHEMBL9245763 | 0.89 | TSHR (0.67) | TSHRFOLH1CA1CA2CA9 | |
| SCHEMBL69352 | 0.87 | TSHR (0.68) | TSHRFOLH1CA1CA2CA9 | |
| SCHEMBL7759867 | 0.86 | TSHR (0.74) | TSHRFOLH1CA1CA2CA9 | |
| SCHEMBL69041 | 0.86 | TSHR (1.00) | TSHRFOLH1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1286448-C | Dentifrice composition comprising a stable low water content phase comprising polyphosphate and ionic active ingredients | PROCTER & GAMBLE (US) | 2006-11-29 | — | — | CN | disclosed |
| CN-1592605-A | Dentifrice composition comprising a stable low water content phase comprising polyphosphate and ionic active ingredients | PROCTER & GAMBLE (US) | 2005-03-09 | — | — | CN | disclosed |