Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17996024 | 0.96 | SMN1; SMN2 (0.48) | SMN1; SMN2POLBMEN1KMT2ALMNA | |
| SCHEMBL8866398 | 0.86 | CYP1A2 (0.48) | P2RX4POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL20570946 | 0.84 | ALDH1A1 (0.52) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL1841464 | 0.79 | CALM1 (0.61) | IDO1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10491650 | 0.79 | KCNH2 (0.48) | P2RX4SMN1; SMN2IDO1POLBLMNA | |
| SCHEMBL2140291 | 0.77 | CALM1 (0.67) | SMN1; SMN2IDO1POLBMEN1KMT2A | |
| SCHEMBL275839 | 0.77 | CALM1 (0.67) | SMN1; SMN2IDO1POLBMEN1KMT2A | |
| SCHEMBL7213235 | 0.77 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL3186379 | 0.76 | ESR1 (0.59) | — | |
| SCHEMBL19880331 | 0.76 | APP (0.42) | IDO1ALDH1A1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113215-A1 | Electroluminescent Materials and Devices | MERCK PATENT GMBH (DE) | 2008-05-15 | — | — | US | claimed |
| EP-2984079-B1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LTD (GB) | 2020-07-01 | — | — | EP | disclosed |
| US-10439147-B2 | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | POWER OLEDS LIMITED (GB) | 2019-10-08 | — | — | US | disclosed |
| US-20180323378-A9 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LIMITED (GB) | 2018-11-08 | — | — | US | disclosed |
| EP-2232611-B1 | BARRIER COATED SUBSTRATE AND ELECTRO-OPTICAL DEVICE | MERCK PATENT GMBH (DE) | 2017-11-01 | — | — | EP | disclosed |
| US-9437828-B2 | Electroluminescent device using azomethine-lithium-complex as electron injection layer | MERCK PATENT GMBH (DE) | 2016-09-06 | — | — | US | disclosed |
| EP-2984079-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | Power Oleds Limited (GB) | 2016-02-17 | — | — | EP | disclosed |
| US-20160035983-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LTD (GB) | 2016-02-04 | — | — | US | disclosed |
| US-9221770-B2 | Compounds having electron transport properties, their preparation and use | MERCK PATENT GMBH (DE) | 2015-12-29 | — | — | US | disclosed |
| EP-2318474-B1 | COMPOUND HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES AND ITS PREPARATION AND USE | MERCK PATENT GMBH (DE) | 2015-05-27 | — | — | EP | disclosed |
| WO-2009090423-A1 | BARRIER COATED SUBSTRATE AND ELECTRO-OPTICAL DEVICE | MERCK PATENT GMBH (DE) | 2009-07-23 | — | — | WO | disclosed |
| US-20090167158-A1 | Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2009-07-02 | — | — | US | disclosed |
| WO-2008081178-A1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008078114-A1 | ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008078115-A1 | PHENANTHROLINE COMPOUNDS AND ELECTROLUMINESCENT DEVICES USING THE SAME | MERCK PATENT GMBH (DE) | 2008-07-03 | — | — | WO | disclosed |
| US-20080113215-A1 | Electroluminescent Materials and Devices | MERCK PATENT GMBH (DE) | 2008-05-15 | — | — | US | disclosed |
| US-20070252108-A1 | Electroluminescent Materials and Devices | MERCK PATENT GMBH (DE) | 2007-11-01 | — | — | US | disclosed |
| EP-1786885-A1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | OLED-T LIMITED (GB) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006090098-A1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | OLED-T LIMITED (GB) | 2006-08-31 | — | — | WO | disclosed |
| WO-2006016176-A1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | OLED-T LIMITED (GB) | 2006-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180323378-A9 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | NAT1, SLCO2A1, SLCO2B1 | P2RX4 1434/4885SMN1; SMN2 3087/4885IDO1 124/4885 |
| US-20070252108-A1 | Electroluminescent Materials and Devices | AAAS, ANXA1, ANXA2 | P2RX4 1984/4885SMN1; SMN2 1804/4885IDO1 3623/4885 |
| US-10439147-B2 | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | NAT1, SLCO2A1, SLCO2B1 | P2RX4 1434/4885SMN1; SMN2 3087/4885IDO1 124/4885 |
| US-20080113215-A1 | Electroluminescent Materials and Devices | AAAS, ACMSD, KCNH1 | P2RX4 1879/4885SMN1; SMN2 3521/4885IDO1 3869/4885 |
| US-20160035983-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | NAT1, SLCO2A1, SLCO2B1 | P2RX4 1434/4885SMN1; SMN2 3087/4885IDO1 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.