Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.38 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20573268 | 0.91 | BCL9 (0.40) | SCN9AMAP4K4FFAR4 | |
| SCHEMBL20573325 | 0.88 | APP (0.42) | SCN9ACHRM3CHRM2CHRM1 | |
| SCHEMBL20573251 | 0.85 | CHRM3 (0.42) | SCN9APTGDR2CHRM3CHRM2CHRM1 | |
| SCHEMBL20573261 | 0.85 | BCL9 (0.44) | SCN9ACHRM3 | |
| SCHEMBL17796980 | 0.84 | PTGDR2 (0.43) | PTGDR2FFAR4 | |
| SCHEMBL20573324 | 0.84 | PDE4D (0.45) | SCN9APTGDR2CHRM3CHRM2CHRM1 | |
| SCHEMBL20573272 | 0.84 | BCL9 (0.44) | SCN9APTGDR2CHRM3NR3C1PGR | |
| SCHEMBL17796967 | 0.84 | CHRM3 (0.38) | SCN9APTGDR2CHRM3CHRM2CHRM1 | |
| SCHEMBL17796961 | 0.83 | CHRM3 (0.40) | SCN9APTGDR2CHRM3CHRM2CHRM1 | |
| SCHEMBL17797027 | 0.83 | CHRM3 (0.41) | SCN9ACHRM3CHRM2CHRM1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029026-B1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | DONG A ST CO LTD (KR) | 2018-12-05 | — | — | EP | claimed |