Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 3/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | KMO | O15229 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MAP2 | P11137 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20573251 | 0.90 | CHRM3 (0.42) | CHRM3CHRM2CHRM1SCN9APTGDR2 | |
| SCHEMBL20573261 | 0.87 | BCL9 (0.44) | BCL9CTNNB1CHRM3LRRK2SLC9A1 | |
| SCHEMBL17796961 | 0.85 | CHRM3 (0.40) | CHRM3CHRM2CHRM1LRRK2SLC9A1 | |
| SCHEMBL20573247 | 0.84 | SCN9A (0.47) | CHRM3CHRM2CHRM1SCN9ANR3C1 | |
| SCHEMBL20573268 | 0.84 | BCL9 (0.40) | BCL9CTNNB1LRRK2SLC9A1SCN9A | |
| SCHEMBL17796967 | 0.83 | CHRM3 (0.38) | CHRM3CHRM2CHRM1LRRK2CTSA | |
| SCHEMBL20573325 | 0.81 | APP (0.42) | CHRM3CHRM2CHRM1CTSASLC9A1 | |
| SCHEMBL20573324 | 0.81 | PDE4D (0.45) | CHRM3CHRM2CHRM1SLC9A1SCN9A | |
| SCHEMBL20573165 | 0.80 | ERN1 (0.49) | LRRK2SLC9A1 | |
| SCHEMBL17797025 | 0.80 | PARP1 (0.42) | SLC9A1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029026-B1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | DONG A ST CO LTD (KR) | 2018-12-05 | — | — | EP | claimed |