Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20573247 | 0.91 | SCN9A (0.47) | SCN9AFFAR4MAP4K4 | |
| SCHEMBL17796980 | 0.90 | PTGDR2 (0.43) | FFAR4GRM2 | |
| SCHEMBL17797023 | 0.88 | ERN1 (0.40) | FFAR4ERN1SLC9A1LRRK2 | |
| SCHEMBL20573261 | 0.87 | BCL9 (0.44) | BCL9CTNNB1SCN9ASLC9A1LRRK2 | |
| SCHEMBL20573165 | 0.86 | ERN1 (0.49) | FFAR4ERN1SLC9A1LRRK2CHEK2 | |
| SCHEMBL17797025 | 0.85 | PARP1 (0.42) | SCN9ASLC9A1PLK4DAPK3CHEK2 | |
| SCHEMBL20573251 | 0.85 | CHRM3 (0.42) | SCN9A | |
| SCHEMBL17797016 | 0.85 | KIF11 (0.51) | SCN9A | |
| SCHEMBL4971993 | 0.84 | TUBB4A (0.36) | BCL9CTNNB1SCN9AFFAR4ERN1 | |
| SCHEMBL20573270 | 0.84 | SLC6A4 (0.50) | GRM2PTGS1SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029026-B1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | DONG A ST CO LTD (KR) | 2018-12-05 | — | — | EP | claimed |