Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | MARK3 | P27448 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20573269 | 0.91 | TUBB4A (0.44) | PARP1SLC9A1SCN9AHPGDSCHEK2 | |
| SCHEMBL20573246 | 0.89 | FABP7 (0.42) | — | |
| SCHEMBL17797025 | 0.88 | PARP1 (0.42) | PARP1SLC9A1SCN9AHPGDSCHEK2 | |
| SCHEMBL20573238 | 0.80 | PTGDR2 (0.45) | SLC9A1SCN9AMEN1KMT2ATUBB4A | |
| SCHEMBL20573244 | 0.80 | PTGDR2 (0.45) | MEN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL20573242 | 0.78 | TUBB4A (0.42) | SLC9A1SCN9AMEN1KMT2ATUBB4A | |
| SCHEMBL3830484 | 0.78 | TUBB4A (0.41) | CHEK2CHEK1MEN1KMT2ATUBB4A | |
| SCHEMBL17796956 | 0.78 | PTGER1 (0.43) | SLC9A1MEN1KMT2A | |
| SCHEMBL20573264 | 0.77 | TUBB4A (0.50) | PARP1SLC9A1MAPK1MEN1KMT2A | |
| SCHEMBL17796943 | 0.77 | PTGDR2 (0.49) | SCN9AKMT2AKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029026-B1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | DONG A ST CO LTD (KR) | 2018-12-05 | — | — | EP | claimed |