SCHEMBL20573269

SCHEMBL20573269

NC(=O)Oc1ccccc1-c1cccc(F)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 2/20 0.44
TUBB P07437 2/20 0.44
TUBA3C P0DPH7 2/20 0.44
TUBA1B P68363 2/20 0.44
TUBA4A P68366 2/20 0.44
TUBB4B P68371 2/20 0.44
TUBB3 Q13509 2/20 0.44
TUBB2A Q13885 2/20 0.44
TUBB8 Q3ZCM7 2/20 0.44
TUBA3E Q6PEY2 2/20 0.44
TUBA1A Q71U36 2/20 0.44
TUBA1C Q9BQE3 2/20 0.44
TUBB6 Q9BUF5 2/20 0.44
TUBB2B Q9BVA1 2/20 0.44
TUBB1 Q9H4B7 2/20 0.44
SLC9A1 P19634 2/20 0.43
PARP1 P09874 1/20 0.42
ADRA2A P08913 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17797025 0.91 PARP1 (0.42) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL20573259 0.91 PARP1 (0.42) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL17796956 0.87 PTGER1 (0.43) SLC9A1MEN1KMT2A
SCHEMBL31448682 0.85 FABP3 (0.49) MAPK1MEN1KMT2AHTT
SCHEMBL20573270 0.83 SLC6A4 (0.50) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL20573246 0.83 FABP7 (0.42)
SCHEMBL17796980 0.83 PTGDR2 (0.43) HTT
SCHEMBL17797004 0.83 MAOA (0.44) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL20573260 0.83 SELL (0.43) PARP1ADRA2AADRA2BADRA2CPLK4
SCHEMBL20573244 0.82 PTGDR2 (0.45) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3029026-B1 NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME DONG A ST CO LTD (KR) 2018-12-05 EP claimed