Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | MMP8 | P22894 | 3/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18893748 | 0.98 | MMP2 (0.42) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL18893730 | 0.96 | MMP2 (0.44) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL20575089 | 0.80 | CA12 (0.39) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL19974195 | 0.79 | CA12 (0.38) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL18893744 | 0.78 | CA12 (0.40) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL14516800 | 0.76 | MMP2 (0.47) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL5670791 | 0.74 | MMP2 (0.50) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL20575012 | 0.72 | SHBG (0.35) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL27769846 | 0.69 | MMP2 (0.42) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL2491379 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180346739-A1 | POLYMERIC FLAME RETARDANT MIXTURES | CLARIANT PLASTICS & COATINGS LTD (CH) | 2018-12-06 | — | — | US | disclosed |