Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 3/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339091 | 0.79 | GLA (0.46) | MYCNR4A1S1PR4S1PR1KDM4E | |
| SCHEMBL31393253 | 0.79 | NPSR1 (0.50) | MYCNR4A1KDM4EALDH1A1LMNA | |
| SCHEMBL31733462 | 0.76 | MYC (0.54) | MYCNR4A1KDM4EALDH1A1LMNA | |
| SCHEMBL10575241 | 0.76 | S1PR4 (0.42) | MYCNR4A1S1PR4S1PR1S1PR5 | |
| SCHEMBL12180605 | 0.75 | ALDH1A1 (0.59) | MYCNR4A1KDM4EALDH1A1LMNA | |
| SCHEMBL26420035 | 0.74 | S1PR4 (0.39) | MYCNR4A1S1PR4S1PR1S1PR5 | |
| SCHEMBL6948406 | 0.73 | ALDH1A1 (0.55) | MYCNR4A1KDM4EALDH1A1LMNA | |
| SCHEMBL28589898 | 0.72 | KDM4E (0.41) | MYCNR4A1KDM4EALDH1A1LMNA | |
| SCHEMBL10574822 | 0.72 | SMN1; SMN2 (0.61) | S1PR4S1PR1S1PR5KDM4EALDH1A1 | |
| SCHEMBL1440318 | 0.72 | MYC (0.42) | MYCNR4A1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349870-B | Process for the preparation of intermediates of compounds which modulate kinase activity | 正大天晴药业集团股份有限公司 | 2020-03-10 | — | — | CN | disclosed |
| US-20180346418-A1 | KINASE ACTIVITY REGULATING COMPOUND INTERMEDIATES PREPARATION METHOD | CENTAURUS BIOPHARMA CO LTD (CN) | 2018-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180346418-A1 | KINASE ACTIVITY REGULATING COMPOUND INTERMEDIATES PREPARATION METHOD | MAP3K6, MAP3K13, MAP3K7 | MYC 910/4885NR4A1 4273/4885S1PR4 3176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.