Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL16666924 | 0.97 | POLB (0.42) | POLBALDH1A1KMT2ATDP1GAA | |
| SCHEMBL21961149 | 0.80 | TSHR (0.57) | POLBALDH1A1KMT2ATDP1GAA | |
| SCHEMBL1904536 | 0.80 | TSHR (0.57) | POLBALDH1A1KMT2ATDP1GAA | |
| SCHEMBL5607279 | 0.80 | LMNA (0.50) | POLBALDH1A1KMT2ATDP1GAA | |
| SCHEMBL133469 | 0.80 | ALDH1A1 (0.52) | POLBALDH1A1KMT2ATDP1GAA | |
| SCHEMBL13951792 | 0.78 | ALDH1A1 (0.50) | POLBALDH1A1KMT2ATDP1GAA | |
| SCHEMBL2955775 | 0.77 | ALDH1A1 (0.54) | POLBALDH1A1KMT2ATDP1GAA | |
| SCHEMBL524784 | 0.77 | POLB (0.45) | POLBALDH1A1KMT2ATDP1GAA | |
| SCHEMBL254364 | 0.77 | ALDH1A1 (0.59) | POLBALDH1A1KMT2ATDP1GAA | |
| Hydrogen Peroxide SCHEMBL9514730 | 0.77 | ALDH1A1 (0.59) | POLBALDH1A1KMT2ATDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180344646-A1 | AMORPHOUS DISPERSION GRANULES AND ORAL DOSAGE FORMS | PATHEON DEVELOPMENT SERVICES INC. (US) | 2018-12-06 | — | — | US | claimed |