SCHEMBL20577248

SCHEMBL20577248

C=CCC1(c2cc[c]cc2)CCCC1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.36
SLC6A3 Q01959 10/20 0.33
SLC6A4 P31645 9/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
SLC6A2 P23975 5/20 0.33
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9231616 0.98 SLC6A3 (0.36) DPP4SLC6A3SLC6A4TSHRHTT
SCHEMBL18668717 0.81 DPP4 (0.57) DPP4SLC6A3SLC6A4TSHRHTT
SCHEMBL251313 0.79 DPP4 (0.55) DPP4SLC6A3SLC6A4SLC6A2MEN1
SCHEMBL6691411 0.78 SLC6A3 (0.41) DPP4SLC6A3SLC6A4SLC6A2
SCHEMBL491176 0.76 ESR1 (0.50) DPP4SLC6A3SLC6A4SLC6A2MEN1
SCHEMBL10408379 0.76 CYP19A1 (0.38) SLC6A3SLC6A4TSHRHTTSLC6A2
SCHEMBL14692734 0.75 SLC6A3 (0.39) DPP4SLC6A3SLC6A4TSHRSLC6A2
SCHEMBL21899382 0.73 SLC6A3 (0.42) DPP4SLC6A3SLC6A4TSHRHTT
SCHEMBL3550695 0.73 DPP4 (0.62) DPP4SLC6A3SLC6A4SLC6A2
SCHEMBL10316574 0.71 DPP4 (0.35) DPP4SLC6A3SLC6A4TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018219797-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2018-12-06 WO disclosed