Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21899382 | 0.94 | SLC6A3 (0.42) | DPP4SLC6A4SLC6A3SLC6A2TSHR | |
| SCHEMBL10316662 | 0.91 | MAOA (0.35) | SLC6A4SLC6A3OPRM1 | |
| SCHEMBL12982361 | 0.81 | CNR2 (0.39) | SLC6A4SLC6A3SLC6A2OPRM1CYP2D6 | |
| SCHEMBL21899362 | 0.79 | SLC6A3 (0.40) | DPP4SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL18185597 | 0.79 | SLC6A4 (0.61) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL10606137 | 0.78 | DPP4 (0.57) | DPP4SLC6A4SLC6A3SLC6A2CHRM2 | |
| SCHEMBL2656480 | 0.76 | CNR2 (0.43) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL12981604 | 0.75 | SLC6A4 (0.36) | SLC6A4SLC6A3SLC6A2OPRM1CYP2D6 | |
| SCHEMBL12981512 | 0.75 | ALDH1A1 (0.40) | DPP4SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL13971687 | 0.75 | SLC6A4 (0.58) | SLC6A4SLC6A3SLC6A2CHRM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2520570-A1 | AMINOPYRIDINE COMPOUND | Ube Industries, Ltd. (JP) | 2012-11-07 | — | — | EP | claimed |
| US-20120259123-A1 | AMINOPYRIDINE COMPOUND | UBE INDUSTRIES, LTD. (JP) | 2012-10-11 | — | — | US | claimed |
| CN-102666490-A | Aminopyridine compound | UBE INDUSTRIES | 2012-09-12 | — | — | CN | claimed |
| US-20120226036-A1 | SUBSTITUTED CARBONYL COMPOUND | UBE INDUSTRIES, LTD. (JP) | 2012-09-06 | — | — | US | claimed |
| EP-2476678-A1 | SUBSTITUTED CARBONYL COMPOUNDS | Ube Industries, Ltd. (JP) | 2012-07-18 | — | — | EP | claimed |
| CN-102548985-A | Substituted carbonyl compounds | UBE INDUSTRIES | 2012-07-04 | — | — | CN | claimed |
| EP-2520570-A1 | AMINOPYRIDINE COMPOUND | Ube Industries, Ltd. (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-20120259123-A1 | AMINOPYRIDINE COMPOUND | UBE INDUSTRIES, LTD. (JP) | 2012-10-11 | — | — | US | disclosed |
| CN-102666490-A | Aminopyridine compound | UBE INDUSTRIES | 2012-09-12 | — | — | CN | disclosed |
| US-20120226036-A1 | SUBSTITUTED CARBONYL COMPOUND | UBE INDUSTRIES, LTD. (JP) | 2012-09-06 | — | — | US | disclosed |
| EP-2476678-A1 | SUBSTITUTED CARBONYL COMPOUNDS | Ube Industries, Ltd. (JP) | 2012-07-18 | — | — | EP | disclosed |
| CN-102548985-A | Substituted carbonyl compounds | UBE INDUSTRIES | 2012-07-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120226036-A1 | SUBSTITUTED CARBONYL COMPOUND | PTGER2, PTGER1, LTB4R2 | DPP4 2869/4885SLC6A4 3612/4885SLC6A3 4210/4885 |
| US-20120259123-A1 | AMINOPYRIDINE COMPOUND | PTGIS, QDPR, PTGIR | DPP4 802/4885SLC6A4 774/4885SLC6A3 1394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.