SCHEMBL20577484

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30483680	1.00	CRBN (0.45)	CRBNDDB1ALOX5SMN1; SMN2KDM4E
	SCHEMBL26449433	0.89	KDM4E (0.37)	CRBNDDB1ALOX5SMN1; SMN2KDM4E
	SCHEMBL22534751	0.85	CRBN (0.46)	CRBNDDB1ALOX5KDM4EALDH1A1
	SCHEMBL22534759	0.85	CRBN (0.46)	CRBNDDB1ALOX5SMN1; SMN2AURKB
	SCHEMBL22534784	0.85	DDB1 (0.56)	CRBNDDB1ALOX5SMN1; SMN2KDM4E
	SCHEMBL22534808	0.83	CRBN (0.44)	CRBNDDB1SMN1; SMN2KDM4EALDH1A1
	SCHEMBL22534760	0.83	CRBN (0.46)	CRBNDDB1ALOX5SMN1; SMN2ALDH1A1
	SCHEMBL22534722	0.83	CRBN (0.46)	CRBNDDB1ALOX5AURKBROCK2
	SCHEMBL30483684	0.83	CRBN (0.46)	CRBNDDB1ALOX5AURKBROCK2
	SCHEMBL22534797	0.83	CRBN (0.46)	CRBNDDB1ALOX5SOD1AURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.