SCHEMBL2057754

SCHEMBL2057754

NC(=O)C1CCCCOC1=O

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 3/20 0.36
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
EPHX1 P07099 1/20 0.33
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33
SIRT1 Q96EB6 3/20 0.31
SIRT2 Q8IXJ6 2/20 0.31
MCL1 Q07820 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2057797 1.00 FKBP1A (0.36) FKBP1AALDH1A1LMNAEPHX1CA1
SCHEMBL2058320 1.00 FKBP1A (0.36) FKBP1AALDH1A1LMNAEPHX1CA1
SCHEMBL2058293 0.94 FKBP1A (0.33) FKBP1AALDH1A1LMNAEPHX1CA1
SCHEMBL2057937 0.94 FKBP1A (0.33) FKBP1AALDH1A1LMNAEPHX1CA1
SCHEMBL2058351 0.94 FKBP1A (0.33) FKBP1AALDH1A1LMNAEPHX1CA1
SCHEMBL2634001 0.85
SCHEMBL2633900 0.85
SCHEMBL1076296 0.85
SCHEMBL6048244 0.81 FKBP1A (0.36) FKBP1AALDH1A1LMNACA1CA9
SCHEMBL3414464 0.79 FKBP1A (0.39) FKBP1ACA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117178085-A air textured yarn 莱卡英国有限公司 2023-12-05 CN claimed
JP-61176657-A None JP disclosed
CN-117178085-A air textured yarn 莱卡英国有限公司 2023-12-05 CN disclosed
CN-116888314-A Nylon 6 fiber, material-recycled polycaprolactone amide resin particles, and method for producing same 东丽株式会社 2023-10-13 CN disclosed
CN-116888314-A Nylon 6 fiber, material-recycled polycaprolactone amide resin particles, and method for producing same 东丽株式会社 2023-10-13 CN disclosed
CN-116356447-A Synthesis process of light-resistant and ultraviolet-resistant nylon fiber 海安县华荣化纤有限公司 2023-06-30 CN disclosed
CN-116356447-A Synthesis process of light-resistant and ultraviolet-resistant nylon fiber 海安县华荣化纤有限公司 2023-06-30 CN disclosed
CN-114249890-B Bio-based polyesteramide and preparation method thereof 南京工业大学 2023-02-21 CN disclosed
CN-115262050-A High-hardness nylon66 high-stretch yarn and hardness detection method thereof 吴江海角工业用布有限公司 2022-11-01 CN disclosed
CN-114249890-A Bio-based polyesteramide and preparation method thereof 南京工业大学 2022-03-29 CN disclosed
CN-110318118-A Flexible highly conductive wool top fiber of one kind and preparation method thereof 海宁泰尔欣新材料有限公司 2019-10-11 CN disclosed
US-20110160303-A1 N-ALKYLCARBONYL-AMINO ACID ESTER AND N-ALKYLCARBONYL-AMINO LACTONE COMPOUNDS AND THEIR USE EDWARD TAK WEI 2011-06-30 US disclosed
EP-2161252-A1 N-Alkylcarbonyl-amino acid ester and N-Alkylcarbonyl-amino lactone compounds and their use Wei, Edward T. (US) 2010-03-10 EP disclosed
US-20080227857-A1 N-Alkylcarbonyl-Amino Acid Ester and N-Alkylcarbonyl-Amino Lactone Compounds and Their Use WEI EDWARD TAK 2008-09-18 US disclosed
US-5691412-A BLEND OF THERMOPLASTIC RESIN WITH BLOCK COPOLYMER RESIN FOR HEAT RESISTANCE TEIJIN LIMITED (JP) 1997-11-25 US disclosed
US-5446109-A Melt reacting while heating in presence of a phenolic compound TEIJIN LIMITED (JP) 1995-08-29 US disclosed
JP-S61176657-A MAGNETIC MATERIAL COMPOSITION HAVING HIGH FLUIDITY DAICEL CHEM IND LTD 1986-08-08 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080227857-A1 N-Alkylcarbonyl-Amino Acid Ester and N-Alkylcarbonyl-Amino Lactone Compounds and Their Use TRPA1, TRPV1, CYSLTR1 FKBP1A 3610/4885ALDH1A1 2618/4885LMNA 1355/4885
US-20110160303-A1 N-ALKYLCARBONYL-AMINO ACID ESTER AND N-ALKYLCARBONYL-AMINO LACTONE COMPOUNDS AND THEIR USE TRPA1, TRPV1, CYSLTR1 FKBP1A 3610/4885ALDH1A1 2618/4885LMNA 1355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.