Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 8/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.45 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16529337 | 1.00 | ADORA2B (0.48) | ADORA2BACHEPIK3CDPOLBADORA3 | |
| SCHEMBL19235546 | 0.89 | ADORA2B (0.50) | ADORA2BACHEPIK3CDPOLBADORA3 | |
| SCHEMBL19235545 | 0.89 | ADORA2B (0.50) | ADORA2BACHEPIK3CDPOLBADORA3 | |
| SCHEMBL16469486 | 0.87 | ADORA2B (0.48) | ADORA2BACHEPIK3CDPOLBADORA3 | |
| Caffeine SCHEMBL5069479 | 0.85 | ADORA2B (0.54) | ADORA2BACHEPIK3CDPOLBADORA3 | |
| Caffeine SCHEMBL5069486 | 0.85 | ADORA2B (0.54) | ADORA2BACHEPIK3CDPOLBADORA3 | |
| SCHEMBL20577697 | 0.77 | SLC7A5 (0.46) | ACHEADORA3USP2LMNACYP1A2 | |
| SCHEMBL20577698 | 0.77 | SLC7A5 (0.46) | ACHEADORA3USP2LMNACYP1A2 | |
| SCHEMBL22679670 | 0.76 | ADORA2B (0.59) | ADORA2BACHEPIK3CDPOLBADORA3 | |
| SCHEMBL20577717 | 0.75 | TYR (0.46) | ACHEADORA3USP2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3412660-B9 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | EA PHARMA CO LTD (JP) | 2021-04-14 | — | — | EP | disclosed |
| EP-3412660-B1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | EA PHARMA CO LTD (JP) | 2020-11-18 | — | — | EP | disclosed |
| EP-3412660-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | EA Pharma Co., Ltd. (JP) | 2018-12-12 | — | — | EP | disclosed |