Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 5/20 | 0.43 |
| ▸ | TPH1 | P17752 | 1/20 | 0.43 |
| ▸ | GRB2 | P62993 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20577697 | 1.00 | SLC7A5 (0.46) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL19235521 | 0.87 | ALDH1A1 (0.38) | PTGS2ALDH1A1ITGB1ITGA4ITGB7 | |
| SCHEMBL19235522 | 0.87 | ALDH1A1 (0.38) | PTGS2ALDH1A1ITGB1ITGA4ITGB7 | |
| SCHEMBL20577715 | 0.87 | SLC7A5 (0.43) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL20577713 | 0.87 | SLC7A5 (0.43) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL20577891 | 0.85 | SLC7A5 (0.43) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL20577894 | 0.85 | SLC7A5 (0.43) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL20578157 | 0.82 | HSD17B10 (0.40) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL20578156 | 0.82 | HSD17B10 (0.40) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL23222700 | 0.81 | PGR (0.31) | ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699008-B | Sulfonamide derivatives and pharmaceutical compositions containing the same | EA制药株式会社 | 2021-10-08 | — | — | CN | disclosed |
| EP-3412660-B9 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | EA PHARMA CO LTD (JP) | 2021-04-14 | — | — | EP | disclosed |
| EP-3412660-B1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | EA PHARMA CO LTD (JP) | 2020-11-18 | — | — | EP | disclosed |
| US-10562898-B2 | Substituted benzenesulfonamides as inhibitors of alpha-4 beta-7 integrin activity | EA PHARMA CO., LTD. (JP) | 2020-02-18 | — | — | US | disclosed |
| US-20190040059-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | EA PHARMA CO., LTD. (JP) | 2019-02-07 | — | — | US | disclosed |
| EP-3412660-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | EA Pharma Co., Ltd. (JP) | 2018-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10562898-B2 | Substituted benzenesulfonamides as inhibitors of alpha-4 beta-7 integrin activity | ITGB4, ITGB7, ITGA4 | SLC7A5 2051/4885PTGS1 3764/4885ALPI 2880/4885 |
| US-20190040059-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | ITGB4, ITGB5, ITGA4 | SLC7A5 1824/4885PTGS1 3067/4885ALPI 2998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.