SCHEMBL20577919

SCHEMBL20577919

C=Cc1cccc(C[Si](C)(C)N([Si](C)(C)C)[Si](C)(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
FAAH O00519 1/20 0.32
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20803553 0.85 TP53 (0.43) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL20786851 0.80 ALDH1A1 (0.41) TP53ALDH1A1TSHRMEN1POLB
SCHEMBL29871077 0.78 TP53 (0.46) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL9715865 0.78 TP53 (0.46) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL9715903 0.78 TP53 (0.46) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL611478 0.78 TP53 (0.46) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL28846228 0.78 TP53 (0.46) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL28202399 0.77 TP53 (0.44) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL19931235 0.76 TP53 (0.38) TP53TDP1FAAH
SCHEMBL6296630 0.75 TP53 (0.43) TP53TDP1ALDH1A1TSHRFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10752721-B2 Elastomeric copolymers based on [bis(trihydrocarbylsilyl)aminosilyl]-functionalized styrene and their use in the preparation of rubbers SYNTHOS DWORY 7 SPOLKA Z ORGANICZONA ODPOWIEDZIALNOSCIA SPOLKA JAWNA (PL) 2020-08-25 US disclosed
US-10723822-B2 [Bis(trihydrocarbylsilyl)aminosilyl]-functionalized styrene and a method for its preparation SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA SPOLKA JAWNA (PL) 2020-07-28 US disclosed
US-20190256624-A1 [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND A METHOD FOR ITS PREPARATION SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) 2019-08-22 US disclosed
EP-3341424-B1 ELASTOMERIC COPOLYMERS BASED ON [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND THEIR USE IN THE PREPARATION OF RUBBERS SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA SPOLKA JAWNA (PL) 2019-03-13 EP disclosed
EP-3341423-B1 [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND A METHOD FOR ITS PREPARATION Synthos Sa (PL) 2018-12-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190256624-A1 [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND A METHOD FOR ITS PREPARATION ADSL, PARN, STS TP53 3767/4885TDP1 2488/4885ALDH1A1 1581/4885
US-10723822-B2 [Bis(trihydrocarbylsilyl)aminosilyl]-functionalized styrene and a method for its preparation ADSL, PARN, STS TP53 3767/4885TDP1 2488/4885ALDH1A1 1581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.