Triethylene Glycol

Triethylene Glycol

SCHEMBL205789

O=C(O)c1ccccc1.O=C(O)c1ccccc1.OCCOCCOCCO

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D

The experimentally established mechanism targets of Triethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.58
DAO P14920 1/20 0.58
NAPRT Q6XQN6 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.52
SRD5A2 P31213 2/20 0.50
CES1 P23141 2/20 0.50
CES2 O00748 1/20 0.50
PKM P14618 1/20 0.50
GAA P10253 1/20 0.50
KMT2A Q03164 4/20 0.47
ALDH1A1 P00352 2/20 0.47
PTK2B Q14289 1/20 0.47
MEN1 O00255 3/20 0.46
TP53 P04637 1/20 0.44
TDP1 Q9NUW8 2/20 0.44
RECQL P46063 1/20 0.43
NR4A1 P22736 1/20 0.43
NR4A2 P43354 1/20 0.43
NR4A3 Q92570 1/20 0.43
RARB P10826 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triethylene Glycol SCHEMBL2112665 1.00 TSHR (0.58) TSHRDAONAPRTSMN1; SMN2SRD5A2
Triethylene Glycol SCHEMBL28076076 1.00 TSHR (0.58) TSHRDAONAPRTSMN1; SMN2SRD5A2
Tetraethylene Glycol SCHEMBL1555416 1.00 TSHR (0.58) TSHRDAONAPRTSMN1; SMN2SRD5A2
Pentaethylene Glycol SCHEMBL8622527 1.00 TSHR (0.58) TSHRDAONAPRTSMN1; SMN2SRD5A2
Tetraethylene Glycol SCHEMBL9137599 1.00 TSHR (0.58) TSHRDAONAPRTSMN1; SMN2SRD5A2
Triethylene Glycol SCHEMBL2442859 1.00 TSHR (0.58) TSHRDAONAPRTSMN1; SMN2SRD5A2
Triethylene Glycol SCHEMBL5730892 1.00 TSHR (0.58) TSHRDAONAPRTSMN1; SMN2SRD5A2
Benzoic Acid SCHEMBL6060002 0.98 TSHR (0.61) TSHRDAONAPRTSMN1; SMN2SRD5A2
Benzoic Acid SCHEMBL148714 0.98 TSHR (0.61) TSHRDAONAPRTSMN1; SMN2SRD5A2
Benzoic Acid SCHEMBL818565 0.98 TSHR (0.61) TSHRDAONAPRTSMN1; SMN2SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2694 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3663344-B1 PLASTICIZER COMPOSITION AND RESIN COMPOSITION INCLUDING THE SAME LG CHEMICAL LTD (KR) 2026-01-28 EP claimed
EP-3342794-B2 PLASTICIZER COMPOSITION AND RESIN COMPOSITION LG CHEMICAL LTD (KR) 2025-08-27 EP claimed
US-12390971-B2 Process and system for blending a plasticizer with a polysaccharide ester polymer CELANESE INTERNATIONAL CORPORATION (US) 2025-08-19 US claimed
US-20250197609-A1 ECOFRIENDLY, BIODEGRADABLE BIOLOGICAL POLYSACCHARIDE COMPOSITION FOR PACKAGING MATERIALS BLUE EVOLUTION, INC. (US) 2025-06-19 US claimed
WO-2025128797-A1 ECOFRIENDLY, BIODEGRADABLE BIOLOGICAL POLYSACCHARIDE COMPOSITION FOR PACKAGING MATERIALS BLUE EVOLUTION, INC (US) 2025-06-19 WO claimed
EP-4558557-A1 COMPOSITION CONTAINING CELLULOSE ESTER POLYMER WITH ENHANCED MELT STRENGTH AGENT Celanese International Corporation (US) 2025-05-28 EP claimed
EP-3923064-B1 ELECTROCHROMIC SOLUTION ESSILOR INT (FR) 2025-05-21 EP claimed
WO-2025075986-A9 HYDROGEL ORAL DELIVERY SYSTEMS AND METHODS SCIENTIFIC HORIZONS CONSULTING LLC (US) 2025-05-15 WO claimed
CN-119894971-A Compositions containing cellulose ester polymers and enhanced melt strength agents 国际人造丝公司 2025-04-25 CN claimed
US-20250129006-A1 PRODUCTION OF BENZOIC ACID FROM A BIOMASS SYENSQO SA (BE) 2025-04-24 US claimed
US-4366273-A Polyester composition with mixed metal ion nucleating agents ALLIED CORPORATION (US) 1982-12-28 US claimed
US-4357268-A NEUTRALIZED DIMER OR TRIMER ACID ALLIED CORPORATION (US) 1982-11-02 US claimed
US-4349503-A CRYSTALLIZATION; SODIUM NITRITE AS A NUCLEATING AGENT ALLIED CORPORATION (US) 1982-09-14 US claimed
US-4340526-A ESTER PLASTICIZERS TO LOWER THE MELT VISCOSITY EASTMAN KODAK COMPANY (US) 1982-07-20 US claimed
US-4336343-A CONTAINING SODIUM CITRATE MORRIS TOWNSHIP, MORRIS COUNTY (US) 1982-06-22 US claimed
US-4284540-A BLENDED WITH COPOLYMERS OF ALPHA OLEFINS AND UNSATURATED GLYCIDYL ESTERS, AND WITH BARIUM SALTS OF FATTY ACIDS TORAY INDUSTRIES, INC. (JP) 1981-08-18 US claimed
EP-0017942-A1 Polyethylene terephthalate molding compositions TORAY INDUSTRIES, INC. (JP) 1980-10-29 EP claimed
US-4172824-A PLASTICIZER EASTMAN KODAK COMPANY (US) 1979-10-30 US claimed
US-4071507-A POLYMERIZATION STAMICARBON, N.V. (NL) 1978-01-31 US claimed
US-4068033-A Heat-releasable decalcomanias and adhesive composition therefor COMMERCIAL DECAL, INC. (US) 1978-01-10 US claimed